After depleting Earth's resources for centuries, humankind's survival requires an exodus to outer space. An international expedition is quickly formed to find a suitable new planet, but when plans go awry, the crew is suddenly stranded without power on a strange planet, where something unimaginable lies in wait.

When an unknown disease wipes out most of the world’s population, a man with unique blood is isolated for study. Fearing for his wife’s safety, he breaks his quarantine – into a world overrun by monstrous Infected and a shadowy agency hunting them down.

All unemployed, Ki-taek's family takes peculiar interest in the wealthy and glamorous Parks for their livelihood until they get entangled in an unexpected incident.