A rich man's son believes himself to be the best kung fu fighter in Canton. Unfortunately, his father, anxious for his son's safety, bribes all his opponents to lose. After a humiliating defeat at the hands of an actor in a traveling theatre company, the son resolves to find a better teacher.

The funny clown Bratislav Metulskie is found dead in circus "Apollo". The retired commissioner 00 Schneider is asked to assume control of the case. Schneider and his aged sidekick Körschgen investigate to find the murderer.

With the accidental discovery of a lethal bio-agent at her research facility, Dr. Christine Ruben decides to double cross her own government by stealing the deadly formula to keep it out of the clutches of the military, whom she doesn't trust. To make her rendezvous with some confederates who promise to get her out of the country, she recruits daredevil driver Judd Pierson and his partner Casey Lee, who are down on their luck and take the job without knowing what they're getting into.

In the middle of a routine patrol, officer Daniel Carter happens upon a blood-soaked figure limping down a deserted stretch of road. He rushes the young man to a nearby rural hospital staffed by a skeleton crew, only to discover that patients and personnel are transforming into something inhuman. As the horror intensifies, Carter leads the other survivors on a hellish voyage into the subterranean depths of the hospital in a desperate bid to end the nightmare before it's too late.