What can two little mice possibly do to save an orphan girl who's fallen into evil hands? With a little cooperation and faith in oneself, anything is possible! As members of the mouse-run International Rescue Aid Society, Bernard and Miss Bianca respond to orphan Penny's call for help. The two mice search for clues with the help of an old cat named Rufus.

A fading southern belle moves in with her sister in New Orleans where her ferocious brother-in-law takes stabs at her sanity.

Francis, a young man, recalls in his memory the horrible experiences he and his fiancée Jane recently went through. Francis and his friend Alan visit The Cabinet of Dr. Caligari, an exhibit where the mysterious doctor shows the somnambulist Cesare, and awakens him for some moments from his death-like sleep.