When the prehistoric warm-water beast the Crocosaurus crosses paths with that cold-water monster the Mega Shark, all hell breaks loose in the oceans as the world's top scientists explore every option to halt the aquatic frenzy. Swallowing everything in their paths -- including a submarine or two -- Croc and Mega lead an explorer and an oceanographer on a wild chase. Eventually, the desperate men turn to a volcano for aid.

In search of a new energy source, Russia accidentally reawakens the Kolossus - a giant robot doomsday device from the Cold War. At the same time, a new Mega Shark appears, threatening global security.