Louise, an unfulfilled divorced woman with regrets, gets the chance to relive her past when she meets a young man who bears an uncanny resemblance, in name and appearance, to her high school sweetheart who died many years before.

Lukas, 20, is a prisoner in his own body. As a pre-op transgendered person, he is constantly finding himself trapped in uncomfortable, compromising positions. His best friend, Ine introduces him to the gay scene in Cologne where he meets the confident and gorgeous, Fabio. The two develop a romantic relationship that tests the boundaries of love. ROMEOS forgoes stereotypes and conventions to offer an honest and humorous examination of the most basic of human conditions: friendship, sex, and love.

Based on a true story of two brothers in 1970's Ohio. It tells of their abandonment by their alcoholic parents and how the brothers turned to each other for support.