Samantha has lived her whole life in different foster homes. Now living in a small town, she never feels like she quite fits in, even with her own current foster family who might adopt her, or the boy who follows her around doing her classwork. So, it’s perhaps natural that she doesn’t know what to do with a curious tagalong little sister named Olivia. One day, Sam callously ditches Olivia, who wanders off into the woods on her own and disappears.

Young art student Hideo paints an unnerving portrait of Tomie, who whispers that she loves him. Inexplicably, he reacts by stabbing her to death with a painting trowel. Two friends, Takumi and Shunichi, arrive on the scene and help him dispose of the body. To cheer him up, the boys take the unwitting murderer to the nearest bar for a party... but a mysterious girl named Tomie shows up, bearing a few odd physical resemblances to the dead girl in the ground.

A man who loses his wife and goes to seclude himself in a cabin in the woods, where strange things happen.

After arguing with his girlfriend, Ali, Tyler lands in the arms of sexy new girl, Holly. The next morning, he finds that not only does Ali agree to take him back, but Holly is a new student at their school and is dead set on her new man.

Though Kevin has evidenced 23 personalities to his trusted psychiatrist, Dr. Fletcher, there remains one still submerged who is set to materialize and dominate all the others. Compelled to abduct three teenage girls led by the willful, observant Casey, Kevin reaches a war for survival among all of those contained within him — as well as everyone around him — as the walls between his compartments shatter apart.