Shiratori Sakuto is 28, but has the intelligence of a 6-year-old boy. He works for Dream Flower Service, a flower distribution centre which provides employment for problem youth. One day, he and a colleague, Yanagawa Ryuichi, delivers a rose bouquet to the apartment building where Mochizuki Haruka lives. Because Haruka does not know that the deliveryman is mentally challenged, she is shocked by his response and tries to call the police. Haruka works for a brain physiology research centre where Professor Hachisuka Daigo has been studying the improvement of mental performance. He has succeeded in lab experiments on a white mouse called Algernon. Sakuto is transformed into a genius through surgery. But Algernon's new intelligence begins to fade, and he dies. Sakuto realises that his genius, too, is destined to leave him.

La Femme Nikita was a Canadian action/drama television series based on the French film Nikita by Luc Besson. The series was co-produced by Jay Firestone of Fireworks Entertainment and Warner Bros.. It was adapted for television by Joel Surnow. The series was first telecast in North America on the USA Network cable channel on January 13, 1997, and ran for five television seasons—until March 2001. The series was also aired in Canada on the over-the-air CTV Television Network. La Femme Nikita was the highest-rated drama on American basic cable during its first two seasons. It was also distributed in some other countries, and it continues to have a strong cult following.