I Am Not An Animal is an animated comedy series about the only six talking animals in the world, whose cosseted existence in a vivisection unit is turned upside down when they are liberated by animal rights activists.

One day, high-school boy Yamada bumps into the beautiful girl Shiraishi on the stairs (literally), and their lips touch as they fall. When they regain their wits, they realize that they have swapped bodies. As time progresses, the two realize that this is not the only mysterious happening in the school.