A jet leaves on a red-eye flight from Los Angeles to Boston. But early in the flight, ten passengers awaken to a startling realization: All of the other passengers have vanished.

The first female US President Sally Sheridan is shot dead by a sniper during her Veterans Day speech. Her assassin narrowly escapes the scene with his life, national security hot on his heels - or so it seems. Three months later, an elderly couple discover the body of a wounded man in a tree, wearing a parachute. The young man cannot remember the slightest thing about his own identity.