Squidbillies is an animated television series about the Cuylers, an impoverished family of anthropomorphic hillbilly mud squids living in the Appalachian region of Georgia's mountains. The show is produced by Williams Street Studios for the Adult Swim programming block of Cartoon Network and premiered on October 16, 2005. It is written by Dave Willis, co-creator of Aqua Teen Hunger Force, and Jim Fortier, previously of The Brak Show, both of whom worked on the Adult Swim series Space Ghost Coast to Coast. The animation is done by Awesome Incorporated, with background design by Ben Prisk.

Viewers go deep into an Alaskan winter to meet six tough and resilient residents as they try to stay one step ahead of storms and man-eating beasts to make it through to spring. The closest neighbor to Sue Aikens is more than 300 miles away. Eric Salitan subsists solely on what he hunts and forages. Chip and Agnes Hailstone catch fish for currency in bartering for supplies, and Andy and Kate Bassich use their pack of sled dogs for transportation.

The story of a 10-year-old girl Dawn Haley whose sibling rivalry with her three brothers is heightened by the fact that they are quadruplets.

Six young people from New York City, on their own and struggling to survive in the real world, find the companionship, comfort and support they get from each other to be the perfect antidote to the pressures of life.

After Portland homicide detective Nick Burkhardt discovers he's descended from an elite line of criminal profilers known as "Grimms," he increasingly finds his responsibilities as a detective at odds with his new responsibilities as a Grimm.

Thanks to his police officer father's efforts, Shawn Spencer spent his childhood developing a keen eye for detail (and a lasting dislike of his dad). Years later, Shawn's frequent tips to the police lead to him being falsely accused of a crime he solved. Now, Shawn has no choice but to use his abilities to perpetuate his cover story: psychic crime-solving powers, all the while dragging his best friend, his dad, and the police along for the ride.

When they were boys, Sam and Dean Winchester lost their mother to a mysterious and demonic supernatural force. Subsequently, their father raised them to be soldiers. He taught them about the paranormal evil that lives in the dark corners and on the back roads of America ... and he taught them how to kill it. Now, the Winchester brothers crisscross the country in their '67 Chevy Impala, battling every kind of supernatural threat they encounter along the way.

The series picks up four years after the events of Terminator 2: Judgment Day with John and Sarah Connor trying to stay under-the-radar from the government, as they plot to destroy the computer network, Skynet, in hopes of preventing Armageddon.

Wednesday Addams is sent to Nevermore Academy, a bizarre boarding school where she attempts to master her psychic powers, stop a monstrous killing spree of the town citizens, and solve the supernatural mystery that affected her family 25 years ago — all while navigating her new relationships.

A group of heroic firefighters at Seattle Fire Station 19—from captain to newest recruit—risk their lives and hearts both in the line of duty and off the clock. These brave men and women are like family, literally and figuratively, and together they put their own lives in jeopardy as first responders to save the lives of others.