A missed confession of love haunts a young man on his best girl friend's wedding day. Sudden appearance of a mysterious Angel enables him to go back in time to regain the love of his life. Will he succeed? A romantic comedy of young Ken who missed a chance to confess his love in the past and ended up attending the wedding of his childhood love. Deep with regret as he helplessly watches the wedding party proceed, suddenly time stops and an Angel appears asking him whether he would like to just start over. Astounded as he is, Ken asks to do so, thereby embarking on a journey that will supposedly change everything. All does not go well however, as fate seems to be a resilient force that refuses to change...

The story is set in an ancient time, when the whole country was covered in thick forests. A mysterious plague breaks out, resulting in countless deaths. A pure young man named Yoshihiko becomes chosen as a hero, and he sets out on a journey in order to save a village. He has two goals – to bring back the legendary plant that can cure the plague, and to rescue his father Teruhiko who left to find the plant but never returned.

Mikoto Misumi is a pathologist at UDI (Unnatural Death Investigation) Lab. She can't stand neglecting unnatural deaths and believes there must be a truth behind the deaths. Team members that work with her are autopsy doctor Kai Nakado, recorder Rokuro Kube, clinical test technologist Yuko Shoji and UDI director Yasuo Kamikura. They work on unnatural death cases and try to reveal the truth behind the deaths.

Shingo Okazaki is a young man devoted to his mother to a degree that's rare in Japan. He's a young fellow who treats his mother with respect, but his tendency to overdo it makes his filial devotion look more like a little fault to those around him. Then, a young woman falls in love with him. She finds it very admirable that he takes such good care of his mother, but is also a bit confused by this fellow who seems to care more for his mother than for his girlfriend.

An ex-gymnastic teacher working as a police detective and a super-elite Tokyo University graduate prosecutor are to become a bizarre buddy. They always clash head-on, but eventually they find themselves sharing the same chemistry within themselves.