Cleopatra, the famed Egyptian Queen born in 69 B.C., is shown to have been brought by Roman ruler Julius Caesar at age 18. Caesar becomes sexually obsessed by the 18 year old queen, beds her, and eventually has a son by her. However, his Roman followers and his wife are not pleased by the union. In fact, as Caesar has only a daughter by his wife, he had picked Octavian as his successor.

The story of a mother who died and begins a 49-day long project of reincarnation, and a husband who has barely begun to live a new life after overcoming the pain of losing his wife. Jo Kang Hwa is a skilled thoracic surgeon. After losing his wife four years ago, he had been working as a single father until he got married again two years ago. While he seems like a caring person, he does not offer a hand nor intervene when needed.

Lim Ju-kyung is a high school student. Since she was little, she has had a complex about her appearance. To hide her bare face, Ju-kyung always wears make-up. Her excellent make-up skills make her pretty and she hides her bare face in front of others. She gets involved with 2 men; Lee Su-ho and Han Seo-jun.